I am experiencing this issue. Running latest build, on Win7 and Mac OSX.
I have a screen shot, but I dont have a site to upload it to. BTW thats a really archaic means of posting images.
The cue in slot 1 is stuck in an "orange" state reading REL and the cue continues to play. The other cues are even in a bundle with the cue in slot 1. I have tried releasing the cue every way I can think of. The only resolution is to restart the software.
I am able to recreate this by mashing buttons on my midicon, basically multiple play buttons at once. I can recreate it every time.